Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities
نویسندگان
چکیده
منابع مشابه
Cardiovascular Risk and the Endocannabinoid System
A number of studies and analyses have illustrated the increased rate of cardiovascular disease conferred by multiple risk factors. 1,2 Up to now, however, the primary focus for addressing cardiovascular risk has been the treatment of each risk factor separately (e.g., LDL cholesterol, hypertension, and diabetes). Major gaps in our overall understanding of the ways in which these individual risk...
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The discovery of the cannabinoid receptors and endocannabinoid ligands has generated a great deal of interest in identifying opportunities for the development of novel cannabinergic therapeutic drugs. Such an effort was first undertaken three decades ago by a number of pharmaceutical industries, but was rewarded with only modest success. However, the newly acquired knowledge on the physiologica...
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The active principle in marijuana, Delta(9)-tetrahydrocannabinol (THC), has been shown to have wide therapeutic application for a number of important medical conditions, including pain, anxiety, glaucoma, nausea, emesis, muscle spasms, and wasting diseases. Delta(9)-THC binds to and activates two known cannabinoid receptors found in mammalian tissue, CB1 and CB2. The development of cannabinoid-...
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Table 2 summarizes the recommendations regarding the use of cardiovascular drugs during pregnancy and lactation.
متن کامل[Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders?].
OBJECTIVE The present review provides a brief introduction into the endocannabinoid system and discusses main strategies of pharmacological interventions. METHOD We have reviewed the literature relating to the endocannabinoid system and its pharmacology; both original and review articles written in English were considered. DISCUSSION Cannabinoids are a group of compounds present in Cannabis...
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ژورنال
عنوان ژورنال: Journal of Pharmacy and Bioallied Sciences
سال: 2011
ISSN: 0975-7406
DOI: 10.4103/0975-7406.84435